GSK2983559 free acid

CAS No. 1579965-12-0

GSK2983559 free acid ( —— )

Catalog No. M26238 CAS No. 1579965-12-0

GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 87 Get Quote
10MG 135 Get Quote
25MG 226 Get Quote
50MG 338 Get Quote
100MG 507 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GSK2983559 free acid
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2).
  • Description
    GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    leucyl-tRNA synthetase; Ras-related GTP-binding protein D (RagD)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1579965-12-0
  • Formula Weight
    538.5
  • Molecular Formula
    C21H23N4O7PS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)S(=O)(=O)c1cc2c(Nc3ccc4scnc4c3)ncnc2cc1OCCOP(O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jong Hyun Kim, et al. Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction. Nat Commun. 2017 Sep 29;8(1):732.
molnova catalog
related products
  • T3Inh-1

    T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 μM. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects.

  • Oxazolone

    Oxazolone has been used as a haptenizing agent which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn’s disease and ulcerative colitis.

  • 1-(3,5-Dichloro-4-fl...

    1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone is an intermediate of Sarolaner.