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GSK2983559 free acid

CAS No. 1579965-12-0

GSK2983559 free acid ( —— )

Catalog No. M26238 CAS No. 1579965-12-0

GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GSK2983559 free acid
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2).
  • Description
    GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    leucyl-tRNA synthetase; Ras-related GTP-binding protein D (RagD)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1579965-12-0
  • Formula Weight
    538.5
  • Molecular Formula
    C21H23N4O7PS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)S(=O)(=O)c1cc2c(Nc3ccc4scnc4c3)ncnc2cc1OCCOP(O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jong Hyun Kim, et al. Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction. Nat Commun. 2017 Sep 29;8(1):732.
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